Acne nodules are hard, pus-filled lesions that occur under the skin. Also referred to as cystic acne, acne nodules do not respond to common acne medications such as benzoyl peroxide and salicylic acid. Moreover, due to the fact that acne nodules occur deep inside the dermis they must be treated by a skincare professional in order to minimize scarring and prevent deeper infections.

Visit a dermatologist. In order to get the best treatment for your acne, a dermatologist must examine your skin and determine what medications and treatments will work best for you.

Try Accutane. This is a powerful oral acne medication that works from within to rid your body of acne nodules. It must be prescribed by a dermatologist as it has serious side effects.

Get a glycolic acid or alpha hydroxy acid (AHA) peel. This is a chemical peel that must be done at a dermatologist’s office. It causes acne-ridden skin to blister and peel off, revealing healthy skin.

Try a cortisone injection. This is an on-the-spot injection administered by a dermatologist that goes directly into the nodule to destroy bacteria and quickly heal the lesion. This is the ideal treatment if you only have one or two acne nodules.

Have the nodules drained by a dermatologist. This treatment is a type of minor surgical procedure in which the nodule is cut open and the pus and bacteria are drained. The lesion then heals within a few days.


  • Make sure to discuss all treatment options with a dermatologist before determining which one is right for you.
    Moisturize your skin daily with an oil-free moisturizer to prevent excessive drying of the skin.

References and Resources

A Guide to Acne Nodule Treatments