Your hands and feet work hard every day—and sometimes, that hard work shows. Repeated friction on your hands or feet, caused by something as simple as your shoe rubbing against your foot or repetitive movements during gardening or weightlifting, can result in a buildup of dead skin cells, or a callus. Reducing this friction is one way to soften the skin, but several remedies can help you rediscover soft and comfortable hands and feet without a trip to the doctor. Both calluses and corns are caused by pressure or friction on your skin, resulting in thickened skin. Their location differs, however. You'll find calluses on the palms of your hands, your thumbs and the soles of your feet. Corns pop up on the tops or sides of your toes. Before you take that rough spot to your doctor, discover potential remedies in your pantry and medicine cabinet.