Mastic gum is an extract from Pistacia lentiscus used in herbal medicine to treat gastrointestinal ulcers, breathing conditions, poor circulation, body aches and infections caused by bacteria and fungus. This supplement poses a risk for side effects in some patients.

Common Side Effects

The common side effect of mastic gum is diarrhea or loose stools, according to the Natural Medicines Comprehensive Database.


Diarrhea caused by mastic gum is most common in children. Your risk for developing diarrhea from mastic gum increases with higher dosages of the supplement.


Diarrhea has the potential to cause a dangerous shortage of fluids in your body, or dehydration. Drinking water and eating clear soups and soft fruits helps replenish lost fluids and electrolytes, reports the National Institute of Diabetes and Digestive and Kidney Diseases.


Because mastic gum is a plant, it is possible to develop an allergic reaction to mastic gum. Symptoms of an allergic reaction include difficulty breathing, chest tightness or pain, hives, rash, itching and inflammation of your skin.


You should not take mastic gum if you are pregnant, nursing or suffer from high blood pressure or cardiovascular disease, according to the Physicians Desktop Reference. Additionally, you should talk to your doctor before beginning a mastic gum regimen, especially if you are taking additional medications or supplements.