Advil & Caffeine

Advil & Caffeine
Written By
Jill Corleone
Jill Corleone
Published: Jul 21, 2011
Updated: Dec 13, 2021
2 minute read

If you're feeling achy or have a headache, Advil and caffeine together may alleviate your discomfort. Advil is the brand name for ibuprofen, a nonsteroidal antiinflammatory drug used for pain relief. Interestingly, caffeine also seems to have analgesic properties, helping to relieve pain. And combining both caffeine and Advil may be more effective at helping your pain than either one by itself. Talk to your doctor about whether combining Advil with caffeine is appropriate for you, as the combination may increase your likelihood of stomach upset, reflux or excessive caffeine intake.

A Useful Combination

According to a study published in the December 2014 issue of "The Cochrane Library," adding caffeine to Advil had small, but significant, analgesic effects. The type of pain studied was tension headaches and pain after dental surgery or childbirth. The type of caffeine studied was the pill form, but converting this to coffee, the amount of caffeine that was effective was approximately 1 cup of coffee. Advil and caffeine may also relieve the symptoms of acute migraine headaches.

Safety and Concerns

Combining Advil and caffeine may not be appropriate for everyone. Both Advil and caffeine can increase stomach upset and gastroesophageal reflux, so the combination may worsen these symptoms. Furthermore, taking Advil and caffeine together does not reduce caffeine’s stimulant effects, so the combination at bedtime may interfere with your sleep. Remember, too, that any caffeine you consume with Advil will add to your total caffeine intake, so be careful that you do not consume too much. According to the December 2014 issue of "The Cochrane Library," caffeine is generally not harmful if you limit your intake to less than 500 mg, or about 5 cups of coffee, per day.

Jill Corleone

Jill Corleone is a registered dietitian and health coach who has been writing and lecturing on diet and health for more than 15 years. Her work has been featured on the Huffington Post, Diabetes Self-Management and in the book "Noninvasive…

Sponsored
LEAFtv Logo

LEAFtv is your destination for food, beauty, style and feel-good living, with how-tos and inspiration for everyday life.

Property of TechnologyAdvice. © 2026 TechnologyAdvice. All Rights Reserved

Advertiser Disclosure: Some of the products that appear on this site are from companies from which TechnologyAdvice receives compensation. This compensation may impact how and where products appear on this site including, for example, the order in which they appear. TechnologyAdvice does not include all companies or all types of products available in the marketplace.