Pomegranate juice is used by some people to prevent or treat certain health disorders, as it has been shown to suppress inflammation and inhibit prostate and breast cancer growth, according to the Memorial Sloan-Kettering Cancer Center. It also appears to provide benefit to some patients with cardiovascular disorders. Side effects are rare.


Pomegranate juice health benefits may be due to antioxidant and anti-atherosclerotic qualities of polyphenols in the fruit.

Allergic Reactions

On rare occasions, people experience allergic reactions to pomegranate juice. When applied to the skin, it can result in itching, swelling, difficulty breathing and a runny nose.


People with diabetes should be careful about consuming large amounts of pomegranate juice because it is high in sugar.

Drug Interactions

Large amounts of pomegranate juice can lower blood pressure, possibly leading to complications for people taking hypertension medication. Other drugs that may interact with pomegranate juice include certain antidepressants, cholesterol-lowering drugs and heart medications.

Product Safety

Anyone who wants to avoid side effects caused by pesticide residue, particularly when drinking large amounts of the juice, should opt for organic pomegranate.